Dietary hexachlorocyclohexane induced changes in blood and liver lipids in albino mice.

Ravinder, P and Srinivasan, K and Radhakrishnamurty, R (1990) Dietary hexachlorocyclohexane induced changes in blood and liver lipids in albino mice. Indian Journal of Experimental Biology, 28 (2). pp. 155-7. ISSN 0019-5189

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Abstract

Dietary intake of technical hexachlorocyclohexane (HCH) by albino mice for 2 weeks (at 400 and 800 ppm) resulted in hyperlipemia. Significant increase in triglycerides, phospholipids and cholesterol fractions of blood was observed in these animals. Dietary intake of gamma-isomer of HCH for 2 weeks (at 200 ppm) did not have any effect on blood lipid profile, but at 400 ppm level produced higher contents of phospholipids and cholesterol. The hepatomegaly produced by dietary technical HCH or gamma-HCH was not accompanied by fatty metamorphosis of liver. Hypertriglyceridemia caused by HCH was accompanied by lower triglyceride levels in liver, suggesting a possible higher rate of secretion from liver.

Item Type:	Article
Uncontrolled Keywords:	hexachlorocyclohexane, dietary intake, blood, liver lipids
Subjects:	500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 26 Pesticide Chemistry 600 Technology > 01 Medical sciences > 09 Human Physiology
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	29 Oct 2021 04:47
Last Modified:	29 Oct 2021 04:47
URI:	http://ir.cftri.res.in/id/eprint/2350

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