Studies on the metabolism of piperine: absorption, tissue distribution and excretion of urinary conjugates in rats.

Bhat, B. G. and Chandrasekhara, N. (1986) Studies on the metabolism of piperine: absorption, tissue distribution and excretion of urinary conjugates in rats. Toxicology, 40 (1). 83-92, 20 ref..

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Abstract

Male albino rats were fed piperine, the major bite factor of black pepper, at a dose of 30 mg (170 mg/kg) by gavage or 15 mg (85 mg/kg) intraperitoneally. About 97% was absorbed irrespective of mode of dosing, 3% was excreted in faeces, but none was detectable in urine. Highest concn. of piperine in the stomach and small intestine was attained at about 6 h. Only traces were detected in serum, kidney and spleen from 30 min to 24 h.

Item Type:	Article
Uncontrolled Keywords:	ALKALOIDS-; piperine, metabolic studies on
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 07 Metabolism 600 Technology > 08 Food technology > 30 Spices/Condiments
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	02 Mar 2018 05:46
Last Modified:	02 Mar 2018 05:46
URI:	http://ir.cftri.res.in/id/eprint/6562

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