![[feed]](/style/images/feed-icon-14x14.png){kind=icon}
Antioxidant and lipid peroxidation activities in rats fed with Aspergillus carbonarius carotenoid.
Anbarasu, K. and Akshatha, Hosahalli Srikanta and Muthukumar, S. P. and Umesh Kumar, S. and Vijayalakshmi, G. (2011) Antioxidant and lipid peroxidation activities in rats fed with Aspergillus carbonarius carotenoid. Food and Chemical Toxicology, 49 . pp. 3098-3103.
![[img]](http://ir.cftri.res.in/style/images/fileicons/application_pdf.png) |
PDF
Food and Chemical Toxicology, Volume 49, Issue 12, December 2011, Pages 3098-3103.pdf - Published Version Restricted to Registered users only Download (218kB) | Request a copy |
Abstract
Effect of feeding partially saturated canthaxanthin (PSC), purified from Aspergillus carbonarius mutant, was studied using four groups of female albino rats (n = 6) for four weeks. While the control group received basal diet ad libitum, , Groups I, II and III were fed with basal diet containing 50, 100 and 250 ppm PSC, respectively. PSC feeding did not cause any significant changes in food intake and there was no gain in body weight either. PSC included in the diet significantly decreased cholesterol in blood. There was 44.75% and 60.54% decrease in LDL-cholesterol in rats fed with 50 and 100 ppm carotenoid. Hepatic ascorbic acid content increased by 44.59% in rats fed with 50 ppm PSC. Dietary PSC at 250 ppm lowered lipid peroxides by 19.49%. Activities of antioxidant enzymes, glutathione transferase and catalase were significantly higher in serum and liver of PSC fed rats compared to the controls. The results suggested that PSC feeding can induce hypocholesterolmic and antioxidant properties in rats.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Aspergillus, Canthaxanthin, Antioxidant,HDL/LDL Rats |
| Subjects: | 500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 04 Fungi 600 Technology > 08 Food technology > 32 Antioxidants |
| Divisions: | Dept. of Biochemistry Food Microbiology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 20 Jan 2012 05:38 |
| Last Modified: | 28 Dec 2016 08:41 |
| URI: | http://ir.cftri.res.in/id/eprint/10536 |
Actions (login required)
 |
View Item |