Identification of bioactive compound from Citrus maxima fruit against carbohydrate-hydrolysing enzymes.

Reshmi, S. K. and Manonmani, H. K. and Manjunatha, J. R. and Shashirekha, M. N. (2018) Identification of bioactive compound from Citrus maxima fruit against carbohydrate-hydrolysing enzymes. Current Science, 114 (10). pp. 2099-2105.

PDF CURRENT SCIENCE, VOL. 114, NO. 10, 25 MAY 2018.pdf - Published Version Restricted to Registered users only Download (245kB) | Request a copy

Abstract

The aim of this study was to identify the bioactive compound of Citrus maxima fruit that targets the enzymes responsible for hyperglycaemia. Preliminary in vitro screening of extracts of fruit parts revealed that juicy segments (ethanol, methanol and aqueous) showed the highest inhibition towards the carbohydrate- hydrolysing enzymes. Further, juicy segment extracts were subjected to preparative HPLC for separation and isolation of compounds. After a series of separations, in vitro analysis and characterization, naringin was identified to be the bioactive compound that is responsible for inhibiting carbohydratehydrolysing enzyme activities. Further application, such as developing food formulations from C. maxima will benefit diabetic populations.

Item Type:	Article
Uncontrolled Keywords:	Bioactive compound, Citrus maxima, carbohydrate- hydrolysing enzymes, hyperglycaemia
Subjects:	600 Technology > 08 Food technology > 16 Nutritive value > 05 Enzymes 600 Technology > 08 Food technology > 24 Fruits > 03 Citrus fruits
Divisions:	Fruit and Vegetable Technology
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	29 Aug 2018 04:33
Last Modified:	29 Aug 2018 04:33
URI:	http://ir.cftri.res.in/id/eprint/13821

Actions (login required)

View Item