Effect of Cosolvents on the Stabilization of Bioactive Peptides from Bovine Milk alpha-casein.

Srinivas, Sistla and Prakash, V. (2008) Effect of Cosolvents on the Stabilization of Bioactive Peptides from Bovine Milk alpha-casein. Protein and Peptide Letters, 15 (4). pp. 371-6. ISSN 0929-8665

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Abstract

Peptides with more than one biological activity are many a times multifunctional peptides. Two peptides with multifunctional properties from alpha (S2)-casein were stabilized in presence of cosolvents for their biological activities like ACE inhibition activity and antioxidant activity. These bioactive peptides in cosolvents were also thermostable. Infra red spectra of peptides in cosolvents reveal no change in the secondary structure in presence of cosolvents. Correlation between sequence, structure and composition of peptides on biological activities were studied.

Item Type:	Article
Uncontrolled Keywords:	alpha-casein, cosolvents, polyols, peptides, stabilization, ACE activity, antioxidant activity
Subjects:	600 Technology > 08 Food technology > 27 Dairy products 500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 25 Peptide Chemistry
Divisions:	Protein Chemistry and Technology
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	28 Sep 2010 10:53
Last Modified:	28 Dec 2011 09:34
URI:	http://ir.cftri.res.in/id/eprint/1788

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