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Characterization, antioxidant, and antimicrobial activity of melanin extracted from nigerseed hulls

Sunil Kumar, B.T. and Sathyendra Rao, B. V. and Swathi, S. and Vanajakshi, V. and Umesh Hebbar, H. and Sridevi Annapurna, Singh (2024) Characterization, antioxidant, and antimicrobial activity of melanin extracted from nigerseed hulls. Food Bioscience, 61. p. 104929.

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Abstract

This study aims to characterize and explore the biological effects of melanin derived from nigerseed (Guizotia abyssinica) hulls, which are inedible. Extracted melanin was selectively soluble in alkali and DMSO. The melanin extract demonstrated robust antioxidant and DPPH radical scavenging activities. It exhibited strong antibacterial effects against foodborne pathogens, as indicated by the zone of inhibition (in mm); Salmonella enterica (40.00 ± 0.00), Staphylococcus aureus (37.33 ± 1.15), Micrococcus luteus (31.67 ± 0.58), Klebsiella oxytoca (31.33 ± 1.15), Escherichia coli (30.33 ± 0.58), and Bacillus cereus (28.33 ± 1.15). For antifungal activity, melanin displayed selectivity, suggesting its potential as a targeted antifungal agent. This research highlights nigerseed byproducts as a cost-effective and promising source for melanin production, showcasing its potential in the pharmaceutical sector as a natural alternative to chemically derived drugs.

Item Type: Article
Uncontrolled Keywords: Melanin pigment Nigerseed FTIR Antioxidant Antibacterial Antifungal
Subjects: 600 Technology > 08 Food technology > 19 Lipids-oils/fats > 01 Oilseeds
600 Technology > 08 Food technology > 32 Antioxidants
Divisions: Food Engineering
Food Safety Analytical Quality Control Lab
Lipid Science and Traditional Foods
Protein Chemistry and Technology
Technology Transfer and Business Development
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 08 Nov 2024 10:54
Last Modified: 08 Nov 2024 10:54
URI: http://ir.cftri.res.in/id/eprint/18445

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