Ability of a solid state fermentation technique to significantly minimize catabolic repression of alpha-amylase production by Bacillus licheniformis M27.

The production of s-amylase by Bacillus licheniformis
M27 in submerged fermentation was completely
inhibited due to catabolic repression in medium
containing 1% glucose. In contrast, the enzyme production
in a solid state fermentation system was 19,550
units/ml extract even when the medium contained 15%
glucose. The peak in enzyme titre was, however, shifted
from 48 to 72 h. The ability of the solid state fermentation
system to significantly overcome catabolic repression
was not known earlier and is probably conferred
by various physico-chemical factors and culture conditions
specific to the system.