Effect of L-ascorbic acid supplementation on the toxicity of Pirimiphos-methyl to albino rats.

Rajini, P. S. and Krishnakumari, M. K. (1985) Effect of L-ascorbic acid supplementation on the toxicity of Pirimiphos-methyl to albino rats. International Journal for Vitamin and Nutrition Research, 55 (4). 421-424; 17 ref..

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Abstract

Male rats weighing 100 to 110 g were given the organophosphorus insecticide pirimiphos-methyl 100 or 200 mg/kg bodyweight daily for 21 days without or with L-ascorbic acid 200 mg/kg 1 h before the insecticide was given. Inhibition of acetylcholinesterase in brain and cholinesterase in plasma by pirimiphos-methyl was less in rats given ascorbic acid than in those not given it. Ascorbic acid and glucuronic acid were increased in urine of rats given pirimphos-methyl.

Item Type:	Article
Uncontrolled Keywords:	Organophosphorus-compounds; toxicity-; ascorbic-acid; supplements-
Subjects:	500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 26 Pesticide Chemistry 600 Technology > 01 Medical sciences > 17 Toxicology
Divisions:	Food Protectants and Infestation Control
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	17 Feb 2022 04:04
Last Modified:	17 Feb 2022 04:04
URI:	http://ir.cftri.res.in/id/eprint/8547

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