Reshmi, S. K. and Manonmani, H. K. and Manjunatha, J. R. and Shashirekha, M. N. (2018) Identification of bioactive compound from Citrus maxima fruit against carbohydrate-hydrolysing enzymes. Current Science, 114 (10). pp. 2099-2105.
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Abstract
The aim of this study was to identify the bioactive
compound of Citrus maxima fruit that targets the
enzymes responsible for hyperglycaemia. Preliminary
in vitro screening of extracts of fruit parts revealed
that juicy segments (ethanol, methanol and aqueous)
showed the highest inhibition towards the carbohydrate-
hydrolysing enzymes. Further, juicy segment
extracts were subjected to preparative HPLC for separation
and isolation of compounds. After a series of
separations, in vitro analysis and characterization,
naringin was identified to be the bioactive compound
that is responsible for inhibiting carbohydratehydrolysing
enzyme activities. Further application,
such as developing food formulations from C. maxima
will benefit diabetic populations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Bioactive compound, Citrus maxima, carbohydrate- hydrolysing enzymes, hyperglycaemia |
| Subjects: | 600 Technology > 08 Food technology > 16 Nutritive value > 05 Enzymes 600 Technology > 08 Food technology > 24 Fruits > 03 Citrus fruits |
| Divisions: | Fruit and Vegetable Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 29 Aug 2018 04:33 |
| Last Modified: | 29 Aug 2018 04:33 |
| URI: | http://ir.cftri.res.in/id/eprint/13821 |
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